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21 Procedure: Precisely weigh 0.05 mg of the glutathione sample, place it in a 10 mL beaker, dissolve it with 2% HPO, transfer it to a 100 mL volumetric flask, and dilute to volume with water

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These modifications are discussed in research literature for their effect on reducing binding affinity to insulin-like growth factor binding proteins, resulting in extended biological half-life in experimental models